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CaféScientifique is a nationwide network of groups for the informal discussion of scientific issues

If you have not received live streaming link, please email secretary Cherry Warne immediately.

Computer problems have resulted in loss of some CaféSci member email addresses

The next meeting is on
Tuesday 12 May 2026
at 7.00pm at Eagle House Hotel
3, Castle Street,
Launceston PL15 8BA

Dr Áine Maguire (formerly University of Plymouth now of Somerset NHS)

& Dr Donnchadh Murphy (University of Plymouth

“Alzheimer's diseas updated”

Over the past decade, Alzheimer's disease research has changed dramatically. It is now possible to detect the biological changes linked to Alzheimer's up to 10 to 15 years before symptoms appear, using blood tests and brain imaging. New treatments are also emerging that may slow the disease, offering real hope for prevention.

However, this progress raises difficult questions. The earlier we try to detect Alzheimer's, the less certain we are about what those results mean. Who will go on to develop dementia, and who won't? And how do we avoid causing undue anxiety or misdiagnosis?

In this talk, Dr Áine Maguire and Dr Donnchadh Murphy will explain what “preclinical Alzheimer's disease” is and why it matters. They will discuss the role of “thinking skills” tests used in Alzheimer's research and clinical practice, and consider their use in this new era of biomarker testing. They will introduce the CoCoA project (Computerised Cognitive Assessment), which aims to develop new types of cognitive tests designed specifically to detect the earliest changes in brain function, and predict future dementia. They will also present the results from the CoCoA project and describe its evolution into the CoCoA-PAD study, an NIHR-funded research programme combining cognitive testing with blood biomarkers and MRI scans to improve early detection. This session will be interactive, with time for questions and discussion.

 

Dr Áine Maguire is a clinical psychologist working in an NHS Stroke Service in Somerset. She trained at the University of Plymouth, where her clinical doctoral research focused on developing and evaluating novel memory tests for early stage Alzheimer's disease. Before qualifying as a clinical psychologist, she worked in clinical and applied research across the UK and Ireland, completing a research doctorate at Trinity College Dublin examining the impact of Co Enzyme Q10 on neuropsychological and clinical outcomes in schizophrenia and schizoaffective disorders.

 

Dr Donnchadh Murphy is a principal clinical neuropsychologist at University Hospitals Plymouth NHS Trust and a senior research fellow at University of Plymouth. He has worked on the Computerised Cognitive Assessment (CoCoA) project since 2015 and was recently awarded a research fellowship to develop and deliver the multi-site CoCoA-PAD trial. The CoCoA-PAD trial specifically looks at the integration of Alzheimer's disease biomarkers, advanced MRI imaging with cognitive assessment, to diagnose the preclinical Alzheimer's disease syndrome.

 

 

Scientifique Young Scientist of the Year - Results

Entries

	Ancient Viruses within the Human Genome Abi Fraser Launceston College
	Have Black Holes affected Our Understanding about the Early Universe ? Jack Squires Launceston College
	Putting the Mouth back in the Body Freya Tonks Bideford College
	Defence & Disorder: understanding Immunity & Autoimmune Diseases Maame Owusuah Amporful Bideford College
	Animal Abilities Emily Brookes Bideford College
	How mobile phone bans impact pupils' education and wellbeing in secondary schools Stamatis Mavroudi-Tayler Launceston College
	Ten Thousand Broken Light Bulbs: The Science of Creativity Florence Castleden Liskeard Community College
	Climate change tipping points: how close are we to irreversible disaster? Matthew Carr Bideford College

 

Judges
Chair: Professor Steve Rowland FRSC C Chem
Professor Colin Webb MBE FRs
Professor Michael N. Moore, BSc (Hons), PhD, FRMS
Dr Alan Malvern MA D Phil M Inst P C Phys AFHEA
Marion McCullagh MVB MRCV
Meg Walker BSc Microbiology and Genetics London PGCE
Dr Alan Whittle

 

CaféScientifique,Launceston

Young Scientist of the Year 2025 Competitions
Tuesday 8 July 7.00pm
Eagle House Hotel, 3 Castle Street, Launceston PL15 8BA

 

RULES

There are only 2 competitions this year:
2025 Young Scientist of the Year
2025 Young Scientist of the Year - Members' Choice
It is essential to read the Annexe below with the rules of each competition

2025 Young Scientist of the Year
Entrants to this competition are automatically considered for the the Members' Choice Competition

RULES

 

1. Object of the CaféScientifique, Launceston Young Scientist of the Year Competition

To give young people aged 15 years or over in full time education studying in local secondary schools (entrants) the opportunity to prepare and present a talk (presentation) on a science or engineering related topic of their choice to the members of CaféScientifique, Launceston (CaféSci) thereby competing for the title of CaféScientifique, Launceston Young Scientist of the Year (competition) normally at its July meeting.

2. Date of Competition

The date of the competition shall be determined by the committee.

3. Rules of Competition

i. The rules of the competition (rules) are set out in clauses 4 - 7 below as amended by the Annexe 2025 (Annexe)

ii. The committee of CaféSci (committee) may change the rules as necessary at a committee meeting.

4. Presentation

i. Each entrant's presentation shall be the result of their own work and research, but they may be mentored under the local “Aspire” programme or any similar scheme.

ii. The topic of the presentation must be finalised and communicated to the CaféSci Chair not less than two weeks before the date of the competition as set out in the Annexe.

iii. No presentation shall be longer than 10 minutes. Longer presentations will be marked down.

iv. All presentations are to be made in person.

5. Judges

i. A board of independent judges (judges) appointed by the committee will judge the competition.

ii. The judges' decision shall be final.

6. Results

The results will be announced at the meeting or as soon as possible thereafter to the entrants and on the News page of the CaféSci website www.cafescilaunceston.org

7. Prizes

i. Money prizes as agreed by the committee and certificates will be awarded to a winner and a runner-up in each category as set out in the Annexe

ii. A Certificate of Participation in the competition will be awarded to all other entrants.

ttachment:

Annexe 2025 see below

 

2025 Young Scientist of the Year - Members' Choice
RULES

1. Object of the CaféScientifique, Launceston Young Scientist of the Year Competition - Members' Choice Prize

To give members of CaféScientifique, Launceston (CaféSci) an opportunity to vote for a winner and runner-up in the above competition (competition) (rules annexed) to show their appreciation of the effort made by the entrants, normally at the July meeting (meeting)

2. Date of Competition

The date of the competition shall be determined by the committee.

3. Rules of Competition

 i. The rules of the competition (rules) are set out in clauses 4 - 7 below as amended by the Annexe 2025 (Annexe)

 ii. The committee of CaféSci may change the rules as necessary at a committee meeting.

4. Members

i. A member of CaféSci email list at the time of the competitions is a member for the purpose of voting.

ii. Only members present at the meeting may vote.

5. Voting

Members shall vote for one winner and one runner up in the competition

6. Results

The results will be announced at the meeting or as soon as practicable thereafter to entrants and on the News page of the CaféSci website www.cafescilaunceston.org

7. Prizes

Money prizes as agreed by the committee and certificates will be awarded to a winner and a runner-up in the competition as set out in the Annexe.

Attachments

Annexe 2025: see below

Annexe 1: Young Scientist of the Year Competition Rules: see above

 

ANNEXE
Forms part of the rules for both competitions

1. Object of this annexe (Annexe)

i. This Annexe may be changed by the Committee (committee) of CaféScientifique, Launceston (CaféSci) at any time prior to its publication to potential entrants for any given year.

ii. This Annexe forms part of the rules (rules annexed) for each of the above competitions (competitions) for the year 2025

2. Date of Competitions

The date of the competitions shall be Tuesday 8 July 2025.

3. Entrants to the competitions for 2025

1. Entries for 2025 shall be invited from the following: Launceston College, Bideford College, Liskeard School & Community College, Tavistock Community College, Budehaven Community School, Saltash Community School, Sir James Smith's Community School Camelford, Callywith College Bodmin, Okehampton College and Callington Community College.

ii. All entrants do so with the explicit permission of their parent or guardian to allow their child's name and photograph to be used in newspaper articles and on the internet connected with reporting and promoting the competitions

4. Competition Closing Dates

Topics of talks for the Young Scientist of the Year Competition to the Chair, Professor S J Rowland s.rowland@plymouth.ac.uk to arrive no later than Monday 23 June 2025

5. Results

The results will be announced at the meeting or as soon as practicable thereafter to entrants, on the News page of the CaféSci website www.cafescilaunceston.org

6. Prizes

Money prizes agreed by the committee for 2025 are as follows:

Young Scientist of the Year: First prize £100.00 Second Prize £75.00

Members' Choice: First prize £50.00 Second Prize £35.00

 

Annexe 1: Young Scientist of the Year Competition Rules: see above

Annexe 2: Members' Choice Prize Rules: see above